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2017•International journal of pediatricsRequires access

Updates on type 2 innate lymphoid cells and allergic diseases

Yiming Zheng

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Abstract

Innate lymphoid cell is a type of immune cells that lineage-negative, but can be stimulated to produce inflammatory cytokines that people discovered in recent years.It can be classified into three classes(ILC1, ILC2, ILC3), according to its different functions.Type 2 innate lymphoid cells(ILC2)have attracted much attention because it is closely related with parasites and asthma and other allergic diseases.This review focuses the ILC2 phenotypes and the discovery, distribution, relationships with disease. Key words: Type 2 innate lymphoid cell; IL-5; IL-13; Asthma

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What this paper is about

Innate lymphoid cell is a type of immune cells that lineage-negative, but can be stimulated to produce inflammatory cytokines that people discovered in recent years.It can be classified into three classes(ILC1, ILC2, ILC3), according to its different functions.Type 2 innate lymphoid cells(ILC2)have attracted much attention because it is closely related with parasites and asthma and other allergic diseases.This review focuses the ILC2 phenotypes and the discovery, distribution, relationships with disease. Key words: Type 2 innate lymphoid cell; IL-5; IL-13; Asthma

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Available abstract

Innate lymphoid cell is a type of immune cells that lineage-negative, but can be stimulated to produce inflammatory cytokines that people discovered in recent years.It can be classified into three classes(ILC1, ILC2, ILC3), according to its different functions.Type 2 innate lymphoid cells(ILC2)have attracted much attention because it is closely related with parasites and asthma and other allergic diseases.This review focuses the ILC2 phenotypes and the discovery, distribution, relationships with disease. Key words: Type 2 innate lymphoid cell; IL-5; IL-13; Asthma

Key concepts: Innate lymphoid cell, Medicine, Immunology, Innate immune system, Phenotype, Asthma, Allergic asthma, Disease

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