MRI findings of Vogt-Koyanagi-Harada syndrome in eye

Objective To characterize the ocular findings on MRI in patients with Vagt-Koyanagi-Harada syndrome (VKHS)and its value for diagnosis. Methods The MRI findings of eyes in 14 patients (7 males, 7 females, age ranged 10-62 years) with VKHS were retrospectively analyzed. Results Choriodai thickening was found bilaterally in all 14 patients with isointense signal on T2 and T1 weighted images. Exudative retinal detachment was found in 6 patients (12 eyes) and 5 cases (10 eyes) showed abnormal thickening and enhancement of iris. Two cases were accompanied with optic neuritis. Homogeneous enhancement of lesions after administration of gadopentetate was observed in 11 patients. Conclusion M RI can characterize the ocular lesions and their extent in patients with VKHS, which makes MRI as a useful method to diagnosis and the follow-up of these patients. Key words: Uveomeningoencephalitic syndrome;  Magnetic resonance imaging