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Serum total protein and protein fractions in depression :Relevance for depression and suicide research

许明智, 龚耀先, 郭新胜, 陈佐明

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Abstract

目的 探讨血清蛋白水平与抑郁和自杀的关系.方法 采用双缩脲法和溴甲酚绿法检测66例抑郁症和36名健康对照的血清总蛋白(TP)和白蛋白(Alb)水平.结果 抑郁症组血清TP(P<0.05)和Alb(P<0.01)水平显著低于健康对照组,且与疾病的严重程度呈显著的负相关关系(r分别为-0.25和-0.26,P均<0.05);内源性抑郁症组血清TP和Alb水平与非内源性抑郁症组相比差异不显著(P均＞0.05);抑郁症有自杀行为者血清TP(P<0.05)和Alb(P<0.01)水平显著低于非自杀行为组.结论 抑郁症血清Alb水平降低,且与疾病的严重程度和自杀有关.

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目的 探讨血清蛋白水平与抑郁和自杀的关系.方法 采用双缩脲法和溴甲酚绿法检测66例抑郁症和36名健康对照的血清总蛋白(TP)和白蛋白(Alb)水平.结果 抑郁症组血清TP(P<0.05)和Alb(P<0.01)水平显著低于健康对照组,且与疾病的严重程度呈显著的负相关关系(r分别为-0.25和-0.26,P均<0.05);内源性抑郁症组血清TP和Alb水平与非内源性抑郁症组相比差异不显著(P均＞0.05);抑郁症有自杀行为者血清TP(P<0.05)和Alb(P<0.01)水平显著低于非自杀行为组.结论 抑郁症血清Alb水平降低,且与疾病的严重程度和自杀有关.

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Available abstract

目的 探讨血清蛋白水平与抑郁和自杀的关系.方法 采用双缩脲法和溴甲酚绿法检测66例抑郁症和36名健康对照的血清总蛋白(TP)和白蛋白(Alb)水平.结果 抑郁症组血清TP(P<0.05)和Alb(P<0.01)水平显著低于健康对照组,且与疾病的严重程度呈显著的负相关关系(r分别为-0.25和-0.26,P均<0.05);内源性抑郁症组血清TP和Alb水平与非内源性抑郁症组相比差异不显著(P均＞0.05);抑郁症有自杀行为者血清TP(P<0.05)和Alb(P<0.01)水平显著低于非自杀行为组.结论 抑郁症血清Alb水平降低,且与疾病的严重程度和自杀有关.

Key concepts: Depression (economics), Relevance (law), Psychology, Psychiatry, Medicine, Political science, Macroeconomics, Economics

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