2009•Chinese Journal of NeuromedicineRequires access

Expression of erythropoietin and it's receptor in brain tumor

Shu Chang Xu

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Abstract

红细胞生成素(erythropoietin,EPO)是调节红细胞生成的细胞因子,近年来研究发现,多种非红细胞生成组织表达红细胞生成素受体(erythropoietin receptor,EPOR),提示EPO具有多种生物活性,有可能成为抗肿瘤细胞增殖治疗及抗血管生成治疗的靶点.Epo在各种肿瘤中的作用逐渐成为研究的热点,尤其近年脑肿瘤的研究渐多,现将EPO及受体在脑肿瘤中的表达进行综述。

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红细胞生成素(erythropoietin,EPO)是调节红细胞生成的细胞因子,近年来研究发现,多种非红细胞生成组织表达红细胞生成素受体(erythropoietin receptor,EPOR),提示EPO具有多种生物活性,有可能成为抗肿瘤细胞增殖治疗及抗血管生成治疗的靶点.Epo在各种肿瘤中的作用逐渐成为研究的热点,尤其近年脑肿瘤的研究渐多,现将EPO及受体在脑肿瘤中的表达进行综述。

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Available abstract

红细胞生成素(erythropoietin,EPO)是调节红细胞生成的细胞因子,近年来研究发现,多种非红细胞生成组织表达红细胞生成素受体(erythropoietin receptor,EPOR),提示EPO具有多种生物活性,有可能成为抗肿瘤细胞增殖治疗及抗血管生成治疗的靶点.Epo在各种肿瘤中的作用逐渐成为研究的热点,尤其近年脑肿瘤的研究渐多,现将EPO及受体在脑肿瘤中的表达进行综述。

Key concepts: Erythropoietin, Erythropoietin receptor, Receptor, Expression (computer science), Internal medicine, Cancer research, Endocrinology, Biology

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