Research advances in HPV vaccines

Cervical cancer is the second largest cause of cancer deaths in women. Epidemiological and laboratory studies overwhelmingly support a necessary role for persistent human papillomavirus( HPV) infection and transcription in cervical carcinogenesis. Along with the development of immunology as well as study on HPV and its pathogenic mechanism, new preventive HPV vaccines have been available in many countries. New progress has also been made in therapeutic HPV vaccines. This paper reviews HPV and the advanced progress in HPV vaccines. Key words: Human papillomavirus; Uterina cervical neoplasms; Papillomavirus vaccines