2005Chinese Journal of NeuromedicineRequires access

Investigation of apoptosis in the mechanism of cerebral vasospasm after subarachnoid hemorrhage

茅磊, 史继新

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Abstract

脑血管痉挛是蛛网膜下腔出血的重要并发症,也是造成患者死亡和致残最重要的原因.脑血管痉挛已经成为临床研究的热点,尤其是近几年在发病机制、诊断和治疗方面取得了很大进展.凋亡不同于坏死,是细胞的程序性死亡.最近的研究表明蛛网膜下腔出血以后脑血管内皮细胞存在有凋亡的发生,而且此现象在血管痉挛形成机制中起着重要的作用.对脑血管痉挛凋亡机制的深入研究,必将有助于临床上防治脑血管痉挛。

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What this paper is about

脑血管痉挛是蛛网膜下腔出血的重要并发症,也是造成患者死亡和致残最重要的原因.脑血管痉挛已经成为临床研究的热点,尤其是近几年在发病机制、诊断和治疗方面取得了很大进展.凋亡不同于坏死,是细胞的程序性死亡.最近的研究表明蛛网膜下腔出血以后脑血管内皮细胞存在有凋亡的发生,而且此现象在血管痉挛形成机制中起着重要的作用.对脑血管痉挛凋亡机制的深入研究,必将有助于临床上防治脑血管痉挛。

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Available abstract

脑血管痉挛是蛛网膜下腔出血的重要并发症,也是造成患者死亡和致残最重要的原因.脑血管痉挛已经成为临床研究的热点,尤其是近几年在发病机制、诊断和治疗方面取得了很大进展.凋亡不同于坏死,是细胞的程序性死亡.最近的研究表明蛛网膜下腔出血以后脑血管内皮细胞存在有凋亡的发生,而且此现象在血管痉挛形成机制中起着重要的作用.对脑血管痉挛凋亡机制的深入研究,必将有助于临床上防治脑血管痉挛。

Key concepts: Subarachnoid hemorrhage, Cerebral vasospasm, Mechanism (biology), Vasospasm, Medicine, Apoptosis, Anesthesia, Cardiology

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