2014•Zhonghua neifenmi daixie zazhiRequires access

Approach to the patient with hypothalamic hamartoma-induced precocious puberty

Wen-sheng Jin, Hongmei Li, Jia Li, Weiguo Xu

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Abstract

We described the clinical presentation,image changes,pathologic manifestation,and hormone data before and after surgical excision in a 2 years-old boy with typical central precocious puberty (CPP) resulted from hypothalamic hamartoma(HH).With literature review,the epidemiologic and clinical features,hormone profile,diagnosis,and therapeutic options of CPP induced by HH were discussed to update the general understandings for the management of this disease. Key words: Hypothalamic disease;  Hamartoma;  Central precocious puberty

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What this paper is about

We described the clinical presentation,image changes,pathologic manifestation,and hormone data before and after surgical excision in a 2 years-old boy with typical central precocious puberty (CPP) resulted from hypothalamic hamartoma(HH).With literature review,the epidemiologic and clinical features,hormone profile,diagnosis,and therapeutic options of CPP induced by HH were discussed to update the general understandings for the management of this disease. Key words: Hypothalamic disease;  Hamartoma;  Central precocious puberty

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Available abstract

We described the clinical presentation,image changes,pathologic manifestation,and hormone data before and after surgical excision in a 2 years-old boy with typical central precocious puberty (CPP) resulted from hypothalamic hamartoma(HH).With literature review,the epidemiologic and clinical features,hormone profile,diagnosis,and therapeutic options of CPP induced by HH were discussed to update the general understandings for the management of this disease. Key words: Hypothalamic disease;  Hamartoma;  Central precocious puberty

Key concepts: Hypothalamic hamartoma, Precocious puberty, Hamartoma, Central precocious puberty, Medicine, Presentation (obstetrics), Endocrinology, Disease

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