Efficacy of ranibizumab combined with photocoagulation on diabetic macular edema

Objective To investigate the efficacy ranibizumab combined with photocoagulation on diabetic macular edema(DME). Methods From February 2014 to November 2014, 52 patients (68 eyes) were selected, and were randomly divided into the two groups, 27 cases (36 eyes) in the control group were given macular grid photocoagulation, while 25 cases (32 eyes) in the observation group were first treated with glass cavity injection licensed resistance, and macular grid photocoagulation was performed in one week after injection. The best corrected visual acuity (BCVA), central macular retinal thickness recess (CMT) changes before and after three mouths treatment in the two groups were observed. Results The BCVA of the observation group(0.23±0.17)was significantly improved compared with that before operation, the difference was significant (P<0.05), and the visual acuity was better than that in the control group(0.19±0.14), the differences were significant (P<0.05). After treatment, the CMT in the two groups was less than that before treatment, and the CMT in the observation group was lower than that in the control group[(310.52±49.36) μm vs.(389.74±131.62)μm], the difference was significant (P<0.05). Conclusions Ranibizumab combined with photocoagulation treatment of diabetic macular edema, postoperative visual acuity was more significant , macular edema absorption effect is more obvious. Key words: Ranibizumab; Photocoagulation; Diabetic retinopathy; Diabetic macular edema