Efficacy of vitrectomy and air tamponade for idiopathic macular hole

Objective To evaluate the clinical efficacy of 25 G vitrectomy combined with air tamponade in the treatment of idiopathic macular hole. Methods A retrospective study. The data of 62 eyes of 62 patients with idiopathic macular hole were analyzed. All patients were randomly divided into two groups, with each group of 31 cases. All cases received 25 G vitrectomy combined with peeling of the inner limiting membrane. After gas fluid exchange, the control group received perfluoropropane(C3F8) tamponade in vitrectomy and the observation group received air tamponade in vitrectomy.The follow-up time was 3 months. Results The difference in the rate of hole closing was not statistically significant between the two groups (P=0.895). In observation group, the time of keeping face-down positioning was significant shorter than that of control group (P=0.011). The difference in visual acuity at 3 months postoperatively was not stastically significant (P=0.487). The difference of rate of complication was not stastistically significant between the two groups (P=0.688). Conclusion Vitrectomy and air tamponade for the treatment of idiopathic macular hole, the absorption of air is faster than that of C3F8 tamponade, which is effective to reduce the time of face-down posture. Key words: Vitrectomy, 25 G; Hole, idiopathic, macular; Tamponade, air