Research progress of killing effect of Newcastle disease virus on tumor cells
Minhong Pang, Zhihong Lu
Abstract
Minhong Pang, Zhihong Lu
Abstract
Selective killing effect of Newcastle disease virus (NDV) on tumor cell makes it a potential anti-cancer agent that is widely studied. In recent years, NDV has become a research hotspot in anti-tumor medicine, while the ability to specifically kill tumor cells is the basis of antitumor drug. The tumor-specific killing characteristics and related mechanisms of NDV are reviewed. Key words: Newcastle disease virus; Tumors; Oncolytic virus
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Selective killing effect of Newcastle disease virus (NDV) on tumor cell makes it a potential anti-cancer agent that is widely studied. In recent years, NDV has become a research hotspot in anti-tumor medicine, while the ability to specifically kill tumor cells is the basis of antitumor drug. The tumor-specific killing characteristics and related mechanisms of NDV are reviewed. Key words: Newcastle disease virus; Tumors; Oncolytic virus
Key concepts: Newcastle disease, Oncolytic virus, Virus, Virology, Tumor cells, Biology, Disease, Cancer research