Analysis of different operation method in treatment of single segmental lumbar degenerative disease

Objective To explore the treatment effects of single segmental lumbar degenerative disease.Methods Ninety-six cases of single segmental lumbar degenerative disease according to clinical prospective study group,the principle of randomized,controlled,parallel computer center system were randomly divided into lines of lumbar posterior decompression and intervertebral fusion with pedicle screw rod fixation and intervertebral fusion treatment group (fusion group) and the lumbar fusion followed by posterior decompression after Coflex dynamic fixed fusion not fusion treatment group (non-fusion group) and 48 cases in each group.Followed up for 2 years.The clinical effect was evaluated by visual analog pain score (VAS) and lumbar dysfunction index (ODI).Range of motion was measured by X-ray film.Results The VAS scores and ODI before operation and 3 months,2 years after operation had no significant difference in two groups (P ＞ 0.05).Range of motion at L3-4,L4-5,L5-S1 at 3 months after operation in non-fusion group (7.1 ± 0.8)°,(6.1 ± 0.8)°,(9.2 ± 0.8)° were higher than those before operation(6.4 ± 0.8)°,(5.3 ± 1.8)°,(7.3 ± 0.8)° (P ＜ 0.05).There was no significant difference at 2 years after operation.Range of motion at L3-4at 3 months after operation in fusion group (8.0 ± 0.7)° was higher than that before operation (6.1 ± 0.6)°(P ＜ 0.05).At 2 years after operation (9.1 ± 0.5)° was higher than 3 months after operation and non-fusion group (P ＜ 0.05).Range of motion at L4-5 was lost.Range of motion at L5-S1 at 3 months after operation in fusion group (9.0 ± 0.6)° was higher than that before operation (7.1 ± 0.7) ° (P ＜ 0.05).Conclusions Fusion and non-fusion fixation have satisfying effects in treatment of single segmental lumbar degenerative disease.Non-fusion fixation has less influence on lumbar segments and could reduce adjacent segment degeneration. Key words: Lumbar vertebrae;  Spinal fusion;  Adjacent segment degeneration