2017•国际医药卫生导报Requires access

CT-guided targeted radiofrequency combined with injection of a small dose of collagenase in treatment of cervical disc herniation

Gang Yu, Zengli Huang, Feng Wang

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Abstract

Objective To explore the therapeutic effect of target radiofrequency combined with the injection of a small dose of collagenase into the disc for cerival disc herniation. Methods One hundred and eight patients with cervical intervertebral disc herniation were randomly divided into a treatment group and a control group. The treatment group were treated with radiofrequency ablation and a small dose of collagenase. The control group were treated with collagenase chemolysis. The JOA scores before and 1 week and 1, 3, and 6 months after the treatment were recorded. The treatment effects were compared between these two groups. Results The JOA scores 1 week and 1, 3, and 6 months after the treatment were better than those before the treatment in both groups and were better in the treatment group than in the control group. The good and excellent rate was higher in the treatment group than in the control group (90.7% vs. 83.3%). Conclusion CT-guided targeted radiofrequency combined with injection of a small dose of collagenase in treatment of cervical disc herniation can increase the accuracy and successful rate of radiofrequency and is more effective than only minimally invasive treatment, so it is worth being clinically generalized. Key words: Cervical intervertebral disc herniation; Radiofrequency; Thermocoagulation; Target; Collagenase; CT-guided

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Objective To explore the therapeutic effect of target radiofrequency combined with the injection of a small dose of collagenase into the disc for cerival disc herniation. Methods One hundred and eight patients with cervical intervertebral disc herniation were randomly divided into a treatment group and a control group. The treatment group were treated with radiofrequency ablation and a small dose of collagenase. The control group were treated with collagenase chemolysis. The JOA scores before and 1 week and 1, 3, and 6 months after the treatment were recorded. The treatment effects were compared between these two groups. Results The JOA scores 1 week and 1, 3, and 6 months after the treatment were better than those before the treatment in both groups and were better in the treatment group than in the control group. The good and excellent rate was higher in the treatment group than in the control group (90.7% vs. 83.3%). Conclusion CT-guided targeted radiofrequency combined with injection of a small dose of collagenase in treatment of cervical disc herniation can increase the accuracy and successful rate of radiofrequency and is more effective than only minimally invasive treatment, so it is worth being clinically generalized. Key words: Cervical intervertebral disc herniation; Radiofrequency; Thermocoagulation; Target; Collagenase; CT-guided

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Available abstract

Objective To explore the therapeutic effect of target radiofrequency combined with the injection of a small dose of collagenase into the disc for cerival disc herniation. Methods One hundred and eight patients with cervical intervertebral disc herniation were randomly divided into a treatment group and a control group. The treatment group were treated with radiofrequency ablation and a small dose of collagenase. The control group were treated with collagenase chemolysis. The JOA scores before and 1 week and 1, 3, and 6 months after the treatment were recorded. The treatment effects were compared between these two groups. Results The JOA scores 1 week and 1, 3, and 6 months after the treatment were better than those before the treatment in both groups and were better in the treatment group than in the control group. The good and excellent rate was higher in the treatment group than in the control group (90.7% vs. 83.3%). Conclusion CT-guided targeted radiofrequency combined with injection of a small dose of collagenase in treatment of cervical disc herniation can increase the accuracy and successful rate of radiofrequency and is more effective than only minimally invasive treatment, so it is worth being clinically generalized. Key words: Cervical intervertebral disc herniation; Radiofrequency; Thermocoagulation; Target; Collagenase; CT-guided

Key concepts: Medicine, Collagenase, Therapeutic effect, Radiofrequency ablation, Surgery, Pulsed radiofrequency, Ablation, Internal medicine

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CT-guided targeted radiofrequency combined with injection of a small dose of collagenase in treatment of cervical disc herniation — Research Paper | ScholarLens