Effect of preemptive analgesia with sufentanil plus spinal anesthesia with ropivacaine on postoperative epidural analgesia

Objective To observe the effect of preemptive analgesia with sufentanil plus spinal anesthesia with ropivacaine on postoperative epidural analgesia.Methods 80 women undergoing gynecilogical surgery were randomly divided into groups C and S, 40 women for each group.Group C received 0.5％ ropivacaine of 3 ml and group S received 0.5％ ropivacaine of 3 ml plus sufentanil of 2.5 μg/ml.The formula in group C was sufentanil of 7.5 μg diluted to 3ml and that in group S was NS of 3ml.Analgetic solution for PCA was 0.125％ ropivacaine plus sufentanil of 0.5 μg/ml,background dose was 2ml/h; PCA bolus dose was 2 ml,and lockout time was 30 min.The analgesic effect,total dosage during PCA,and adverse reactions were observed.Results VAS scores were higher and BCS scores were lower in group C than in group S.The scores for postoperative pain on hours 4,8,12,and 24 hour were lower in group S than in group C.The D1/D2radio of more than 5 was greater in group C than in group S.The total dosage during PCA was larger in group C than in group S.The adverse reactions were fewer in group S than in group C.Conclusions Preemptive analgesia with sufentanil plus spinal anesthesia with ropivacaine can relieve postoperative pain,increase comfort in patients,reduce the total dosage ofPCA,and decrease the incidence of adverse reactions. Key words: Sufentanil; Ropivacaine; Spinal anesthesia; Preemptive analgesia; Epidural analgesia