A clinical analyses of neonatal sepsis caused by Klebsiella pnemnoniae

Objective To study the clinical characteristics and the drug sensitivity of neonatalsepticemia caused by Klebsiella pneumoniae in order to provide the evidences for the diagnosis and treatment. Methods A retrospective analysis including clinical data and drug sensitivity results was made in 30 neonates with septicemia caused by Klebsiella pneumoniae. Results Neonatal septicemia caused by Klebsiella pneumoniae could be damaging to many organs. There were 8 ESBLs strains in 30 Klebsiella pneumoniae strains( was 26.7% ) ,and22 are negative ESBLs starins( was 73.3% ). It was 100% of the Klebsiella pneumoniae strains were sensitive to carbapenems such as inipenem and panipenem, but there were 90% and 70% to each gentamicin and ciprofloxacin. Klebsiella pneumoniae were not sensitve to much of penicillin and cephalosporin. Conclusion The incidence of neonatal septicemia caused by Klebsiella pneumoniae wes higher than ever, and many of them were infected in hospital. Part of them were extended ESBLs and insensitive to the commonly used antibiotices. It is suggested the antibiotics should be used according to drug senitivity. Key words: Neonate;  Septicemia;  Klebsiella pneumoniae