2007•Int J GenetRequires access

Telomere, Telomerase, Aging and Cancer

张晓辉, 张建宁

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Abstract

端粒和端粒酶与细胞增殖密切相关,在衰老和癌变过程中发挥重要作用.端粒的结构和长度变化、端粒酶的表达水平在众多相关蛋白所组成的复杂调控网络的作用下保持平衡.端粒酶也通过非端粒依赖性机制发挥细胞保护作用,可以促进干细胞激活和增殖。

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What this paper is about

端粒和端粒酶与细胞增殖密切相关,在衰老和癌变过程中发挥重要作用.端粒的结构和长度变化、端粒酶的表达水平在众多相关蛋白所组成的复杂调控网络的作用下保持平衡.端粒酶也通过非端粒依赖性机制发挥细胞保护作用,可以促进干细胞激活和增殖。

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Available abstract

端粒和端粒酶与细胞增殖密切相关,在衰老和癌变过程中发挥重要作用.端粒的结构和长度变化、端粒酶的表达水平在众多相关蛋白所组成的复杂调控网络的作用下保持平衡.端粒酶也通过非端粒依赖性机制发挥细胞保护作用,可以促进干细胞激活和增殖。

Key concepts: Telomere, Telomerase, Cancer, Genetics, Biology, DNA, Gene

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