2013•Zhonghua neifenmi daixie zazhiRequires access

Effect of curcumin on expression of resistin mRNA in rats with insulin resistance

Shuting Bai, Zhao Xiao-juan, Fan Wang, Wei Chen, Nannan Wang

Abstract

By feeding rats with high-fat diet insulin resistant models were induced.Some of the models were treated with intragastric administration of curcumin,then the effects were evaluated by hyperinsulinaemic-euglycaemic clamp technique.Curcumin reduced the level of serum resistin and the expression of resistin mRNA in adipose tissue,and thus ameliorated insulin resistance in rats. Key words: Insulin resistance ; Hyperinsulinaemic-euglycaemic clamp ; Curcumin ; Resistin

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Available abstract

Key concepts: Resistin, Internal medicine, Endocrinology, Insulin resistance, Curcumin, Adipose tissue, Insulin, Glucose clamp technique