Efficacy comparison of transplantation of fresh amnion vs biological amnion for the treatment of recurrent pterygium

Objective To discuss recurrent pterygium effectiveness of fresh amnion vs biological amnion transplantation.Methods All eyes received the same antibiotics and anti-inflammation eye drops after operation.Forty cases with pterygium (60 eyes) were randomly divided into two groups,and every group had 30 eyes.One group received transplantation of fresh amnion followed by excision of pterygium,and the other group was subjected to biological amnion transplantation followed by excision of pterygium.All patients were followed up for 1 day,1 week,1 month,3 months after surgery,and the visual acuity,graft survival,complications were observed and compared.Resuits The postoperative visual acuity of both groups improved significantly (P ＜0.05).The corneal epthellium healing was at (6.19±0.65) day in the fresh amnion group,while at (6.22±0.63) day in the biological amnion group.The differences were not statistical significant between two groups (P ＞0.05).One eye recurrence was noted in the fresh amnion group,the recurrence rate was 3.33％.Two eyes recurrence were noted in the biological amnion group,the recurence rate was 6.67％.The differences were not statistical significant between two groups (P ＞0.05).Conclusions Both flesh amnion and biological amnion transplantation can be effective for the treatment of recurrent pterygium and ocular surface reconstruction,the efficacy has no significant difference between the two methods. Key words: Pterygium ;  Amnion transplantation ;  Treatment ;