2017•International Journal of SurgeryRequires access
Interferon regulatory factor 7 and tumor
Enliang Li
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Abstract
Interferon regulatory factor 7 is originally identified in the context of Epstein-Barr virus infection, and has play a key role in regulator of type Ⅰ interferons. Aberrant production of type Ⅰ interferons is associated with many types of diseases such as cancers and autoimmune disorders. Furthermore, mounting evidence has shed light on the importance of interferon regulatory factor 7, which is a multifunctional transcription factor, not only regulate the response of inflammation and immune in body, but also regulate others biological functions such as tumor formation, cell invasion and so on. The article has reviewed the progression of both interferon regulatory factor 7 and tumor.
Key words:
Iinterferon; Interferon regulatory factor 7; Neoplasms