Assessment of left ventricular hemodynamics and systolic function in patients with apical aneurysm after percutaneous ventricular restoration by echocardiography

Objective To evaluate the changes of left ventricular hemodynamics and systolic function in patients with apical aneurysm after percutaneous ventricular restoration(PVR) by echocardiography. Methods Fifty patients with apical aneurysm were divided into PVR group (25 cases) and conservative treatment group(control group, 25 cases). Two-dimensional transthoracic echocardiography(2D-TTE) combined with real-time three-dimensional transesophageal echocardiography(RT-3DTEE) were applied for all the subjects in PVR group on preoperative, one week after operaction, three months after operaction and in control group on initial stage of prevent ventricular remodeling therapy, one week after therapy, three months after therapy to obtain left ventricular end-diastolic diameter(LVEDD), left ventricular end-systolic diameter(LVSDD), left ventricular end-diastolic volume(EDV), end-systolic volume(ESV), left ventricular ejection fraction(LVEF), left ventricular fractional shortening(LVFS), body surface area(BSA), stroke volume(SV), stroke volume index(SVI), cardiac output(CO), cardiac output index(CI). Results There were significant differences in all parameters(P 0.05). Compared with preoperative, there was no difference in all parameters in the following one week after operaction(P>0.05), there was significant increase in SV and significant reduce in LVEDD and EDV (P 0.05). For the control group there was no significant difference between initial stage of prevevt ventricular remodeling therapy and in the following one week or three months after operaction. Conclusions PVR has a definite effect on left ventricular hemodynamics and systolic function in patients with apical aneurysm in the short term, while 2D-TTE and RT-3DTEE provides a reliable basis for clinical to evaluate the effect of the PVR. Key words: Echocardiography; Apical aneurysm; Percutaneous ventricular restoration; Ventricular function, left; Hemodynamics