Large-volume whole lung lavage in treatment of pulmonary alveolar proteinosis

Objective To evaluate the efficacy and safety of large-volume whole lung lavage in the treatment of pulmonary alveolar proteinosis (PAP) through double lumen tracheal intubation and ventilation under general anesthesia. Methods The clinical data of three cases of PAP who were confirmed and received large-volume whole lung lavage in Meizhou People′s Hospital from May 2016 to May 2018 were retrospectively summarized and analyzed. Results After large-volume whole lung lavage, the three patients were all survived with slight complications, and their clinical symptoms, blood gas analysis, lung function and imaging lesions were significantly improved. Conclusions Large-volume whole lung lavage is an effective and safe therapeutic method in the treatment of PAP. Key words: Large-volume; Whole lung lavage; Pulmonary alveolar proteinosis