2010Int J Radiat Med Nuel MedRequires access

Progress of study on the molecular imaging and targeted therapy in CD20 of non Hodgkin' s lymphoma

Lin Zha, Shibin Feng, Qianwei Li

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Abstract

The molecular imaging and targeted therapy with radiolabeled anti-CD20 monoclonal antibody or recombinant anti-CD20 monoclonal antibody fragments is the effective methods to improve the survival rate for non-Hodgkin' s lymphoma (NHL). This article reviews the biological characteristics of CD20 and the immunotherapy, radioimmunotherapy, radioimmunoimaging with anti-CD20 monoclonal antibody for NHL. Key words: Non-Hodgkin' s lymphoma; Cluster of differentiation 20; Rituximab; Immunotherapy; Radioimmunoimaging

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What this paper is about

The molecular imaging and targeted therapy with radiolabeled anti-CD20 monoclonal antibody or recombinant anti-CD20 monoclonal antibody fragments is the effective methods to improve the survival rate for non-Hodgkin' s lymphoma (NHL). This article reviews the biological characteristics of CD20 and the immunotherapy, radioimmunotherapy, radioimmunoimaging with anti-CD20 monoclonal antibody for NHL. Key words: Non-Hodgkin' s lymphoma; Cluster of differentiation 20; Rituximab; Immunotherapy; Radioimmunoimaging

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Available abstract

The molecular imaging and targeted therapy with radiolabeled anti-CD20 monoclonal antibody or recombinant anti-CD20 monoclonal antibody fragments is the effective methods to improve the survival rate for non-Hodgkin' s lymphoma (NHL). This article reviews the biological characteristics of CD20 and the immunotherapy, radioimmunotherapy, radioimmunoimaging with anti-CD20 monoclonal antibody for NHL. Key words: Non-Hodgkin' s lymphoma; Cluster of differentiation 20; Rituximab; Immunotherapy; Radioimmunoimaging

Key concepts: Radioimmunotherapy, Monoclonal antibody, Lymphoma, Rituximab, CD20, Non-Hodgkin's lymphoma, Immunotherapy, Monoclonal antibody therapy

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