Molecular makers of DNA methylation in early diagnosis of lung cancer
Wenbin Liu
Abstract
Wenbin Liu
Abstract
DNA methylation is known as an important molecular mechanism for tumorigenesis.Studies find that CpG islands methylation of the promoter regions of several tumor suppressor genes is an early event in the process of lung cancer,which is significant for early diagnosis and reducing morbidity and mortality of lung cancer. Key words: DNA methylation; Lung neoplasms; Early diagnosis
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DNA methylation is known as an important molecular mechanism for tumorigenesis.Studies find that CpG islands methylation of the promoter regions of several tumor suppressor genes is an early event in the process of lung cancer,which is significant for early diagnosis and reducing morbidity and mortality of lung cancer. Key words: DNA methylation; Lung neoplasms; Early diagnosis
Key concepts: DNA methylation, Lung cancer, Carcinogenesis, Methylation, Cancer research, Biology, CpG site, Suppressor