2008•国际外科学杂志Requires access
Diagnose and treatment of gastrointestinal stromal tumor
Xun Gong, Zongyou Chen, Jianbin Xiang
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Abstract
Gastrointestinal stromal tumors are rare tumors of alimentary tract and originated from the interstitial Cajal cells,with acquired mutation of KIT(CD117).Surgery is the main therapy for resectable tumors,while imatinib,a small-molecule inhibitor of receptor of tyrosine kinase,plays an important role in treating metastatic and recurrent tumors.
Key words:
gastrointestinal stromal turmor; imatinib; diagnosis; treatment