Application of bundle intervention therapy in preventing ventilator associated pneumonia in ICU

Objective To examine the effect of bundle intervention therapy to prevent mechanically ventilated patients from ventilator associated pneumonia （VAP） after thoracic surgery. Methods 81 mechanically ventilated patients after thoracic surgery from January 2007 to December 2008 were selected as the control group, while 109 patients from January 2009 to November 2011 were selected as the intervention group. The control group received conventional nursing, while the intervention group received bundle intervention in addition, which included semi lying position （30-45 degrees）, closed suctioning, continuous aspiration of subglottic secretion, strict execution of hand hygiene, daily waking-up, assessment after extubation, early enteral nutrition, prevention of deep vein thrombsis and peptic ulcer, etc. The incidence rate of VAP was analyzed and compared between two groups. Results The incidence rate of VAP in the intervention group was 8.26%, obviously lower than that in the control group which was 20.99%. The difference was statistically significant （χ2 = 6. 376, P 〈 0. 05 ）. Conclusions Bundle intervention therapy can effectively reduce the incidence rate of VAP in mechanically ventilated patients from VAP after thoracic surgery, and is worthy of clinical application. Key words: Bundle intervention therapy;  Ventilator associated pneumonia;  Mechanically ventilation;  ICU