2004Zhongguo jiceng yiyaoRequires access

Changes in serum high-sensitivity C-reactive protein and lipoprotein levels in patients with acute coronary syndrome and their responses to atorvastatin

陈炳华, 李毓仁, 黄俊, 程芳洲, 李俊明

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Abstract

目的 探讨急性冠脉综合征(ACS)患者血清高敏C-反应蛋白(Hs-CRP)、血脂水平变化及阿托伐他汀的干预情况.方法 69例ACS随机分为阿托伐他汀组(40例)和常规治疗组(29例),治疗前后分别测定Hs-CRP、TC、TG、LDL、HDL,另30例健康人为对照.结果与对照组比较ACS患者Hs-CRP水平明显升高,且与心肌损害程度密切相关.阿托伐他汀治疗2周,能明显下调ACS患者的Hs-CRP水平.结论血清Hs-CRP水平与ACS的发生、程度密切相关,阿托伐他汀的抗炎作用在ACS的早期治疗中有重要意义。

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目的 探讨急性冠脉综合征(ACS)患者血清高敏C-反应蛋白(Hs-CRP)、血脂水平变化及阿托伐他汀的干预情况.方法 69例ACS随机分为阿托伐他汀组(40例)和常规治疗组(29例),治疗前后分别测定Hs-CRP、TC、TG、LDL、HDL,另30例健康人为对照.结果与对照组比较ACS患者Hs-CRP水平明显升高,且与心肌损害程度密切相关.阿托伐他汀治疗2周,能明显下调ACS患者的Hs-CRP水平.结论血清Hs-CRP水平与ACS的发生、程度密切相关,阿托伐他汀的抗炎作用在ACS的早期治疗中有重要意义。

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Available abstract

目的 探讨急性冠脉综合征(ACS)患者血清高敏C-反应蛋白(Hs-CRP)、血脂水平变化及阿托伐他汀的干预情况.方法 69例ACS随机分为阿托伐他汀组(40例)和常规治疗组(29例),治疗前后分别测定Hs-CRP、TC、TG、LDL、HDL,另30例健康人为对照.结果与对照组比较ACS患者Hs-CRP水平明显升高,且与心肌损害程度密切相关.阿托伐他汀治疗2周,能明显下调ACS患者的Hs-CRP水平.结论血清Hs-CRP水平与ACS的发生、程度密切相关,阿托伐他汀的抗炎作用在ACS的早期治疗中有重要意义。

Key concepts: Medicine, Atorvastatin, Acute coronary syndrome, C-reactive protein, Internal medicine, Cardiology, Lipoprotein, Sensitivity (control systems)

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Changes in serum high-sensitivity C-reactive protein and lipoprotein levels in patients with acute coronary syndrome and their responses to atorvastatin — Research Paper | ScholarLens