The clinical research about physical antibacterial material in prevention and treatment of ureteral stent related urinary tract infections

Objective Through inserting the ureteral stent covered with physical antimicrobial film, to investigate the roles of physical antibacterial material in preventing and treating infection caused by indwelling ureteral stent. Methods 120 cases were randomly divided into two groups: observation group and control group. The ureteral stent covered with physical antimicrobial film was placed into the ureter after ureteroscopy lithotripsy in observation group. And in control group, the ureteral stent not covered with physical antimicrobial film was inserted into the ureter after ureteroscopy lithotripsy. The ureteral stents were from the same company and had the same assignment. The infection related to the ureteral stent indwelling was compared between two groups after operation. Results Patients in the observation group,3,7,14,28 days after the operations the incidence of urinary tract infection were 3.3%, 6.7%, 6.7% and 6.7% respectively. In control group, the incidence of urinary tract infection were 6.7%, 20.0%, 30.0% and 43.3% respectively after the operations 3, 7, 14 and 28 days. The urinary tract infection rate at 3rd day post- operations in the observation group and control group had no significant difference. At 7th, 14th, and 28th day post- operation, the urinary tract infection rate in the observation group was lower than in the control group obviously(P 0.05).At 7th, 14th,and 28th day post- operation, the CRP, PCT and urine white blood cell count were reduced in the observation group as compared with those in the control group (P< 0.05). Conclusion The clinical studies confirmed that the ureteral stent covered with physical antimicrobial film can effectively avoid and reduce the infection related to ureteral stent indwelling. Key words: Urinary infection; Antibacterial material; Ureteral calculus