Analysis of epidemiological characteristics of hemorrhagic fever with renal syndrome in Zhejiang Province, China, 2010-2014

Objective To analyze the epidemic situation of hemorrhagic fever with renal syndrome (HFRS) and the population distribution and virus carrying status of the hosts in Zhejiang Province, China, from 2010 to 2014, and to provide scientific evidences for establishing further prevention and control measures. Methods Data on HFRS were collected from the Chinese Disease Reporting System, and descriptive epidemiological method was used to analyze the epidemiological characteristics of HFRS. Rodents were captured by night trapping in five HFRS monitoring sites in Zhejiang Province. Lung and serum samples were collected for detection of hantavirus antigen and antibody using an immunofluorescence assay, and the distribution of rodent population and virus carrying status in Zhejiang Province were analyzed. Results Cases were reported from 2010 to 2014 in Zhejiang Province (463, 539, 498, 521 and 384 cases, respectively), and 3 dead cases were reported in 2010. The cases were mostly seen in five cities, Ningbo, Taizhou, Shaoxing, Lishui and Quzhou (611, 535, 336, 305 and 229 cases, respectively). There were two peaks of incidence, one in spring (May - June) and the other in winter (November - December). The high risk age group of HFRS was 25 - 0.05). Conclusion From 2010 to 2014, in Zhejiang Province, the situation of HFRS epidemic is relatively stable; in key districts and populations, comprehensive measures should be taken to control the epidemic. Key words: Hemorrhagic fever with renal syndrome; Surveillance; Data analysis; Epidemiological characteristics