2017•国际医药卫生导报Requires access
Metoprolol combining diltiazem for patients with coronary heart disease with unstable angina pectoris
Lin Li
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Abstract
Objective
To study the effect of metoprolol combining diltiazem for patients with coronary heart disease with unstable angina pectoris.
Methods
78 patients with coronary heart disease with unstable angina pectoris treated at our hospital were selected and randomly divided into a control group and an observation group, 39 cases for each group. The control group were treated with metoprolol and the observation group metoprolol and diltiazem. The clinical efficacies were compared between these two groups. The cardiac function [left ventricular ejection fraction (LVEF)] in both groups was measured before and after treatment.
Results
The total effective rate was 94.87% in the observation group and was 76.92% in the control group, with a statistical difference (χ2=5.186, P<0.05). After treatment, the LVEF was higher in the observation group than in the control group, with a statistical difference (P<0.05).
Conclusions
Metoprolol combining diltiazem for patients with coronary heart disease with unstable angina pectoris can improve the patients’ cardiac function and is clinically and significantly effective.
Key words:
Diltiazem; Metoprolol; Coronary heart disease with unstable angina pectoris