黄海军, 盛吉芳
Abstract
肝细胞和肝星形细胞(hepatic stellate cell,HSC)的凋亡与肝纤维化的形成、发展和减退有关.肝细胞凋亡产生的凋亡小体被吞噬细胞吞噬,且肝细胞凋亡本身可引起或加重炎症,均导致肝纤维化发生;HCS则通过细胞凋亡来减退肝纤维化.因此,肝细胞和肝星形细胞凋亡对肝纤维化有重要作用。
A significance statement is not available in the OpenAlex record.
A contribution statement is not available in the OpenAlex record.
Method details are not available in the OpenAlex metadata.
Findings are not separately available in the OpenAlex metadata.
Limitations are not available in the OpenAlex metadata.
Application details are not available in the OpenAlex metadata.
肝细胞和肝星形细胞(hepatic stellate cell,HSC)的凋亡与肝纤维化的形成、发展和减退有关.肝细胞凋亡产生的凋亡小体被吞噬细胞吞噬,且肝细胞凋亡本身可引起或加重炎症,均导致肝纤维化发生;HCS则通过细胞凋亡来减退肝纤维化.因此,肝细胞和肝星形细胞凋亡对肝纤维化有重要作用。
Key concepts: Fibrosis, Liver fibrosis, Apoptosis, Medicine, Computer science, Pathology, Biology, Genetics