Efficacy of Chinese alleviating pain capsule (中药止痛胶囊) combined with diclofenac sodium suppository for postoperative analgesia in patients with fracture

Objective To observe the effects of Chinese alleviating pain capsule (中药止痛胶囊) combined with diclofenac sodium suppository in postoperative analgesia of patients with fracture. Methods One hundred patients of both sexes with fracture, aged 21-73 years in Zhengzhou Renji Hospital from April 2016 to June 2017 were collected, and they were divided into diclofenac sodium group and combined group according to the single blind selection method, with fifty cases in each group. The patients were given diclofenac sodium suppository in diclofenac sodium group, while the patients took Chinese alleviating pain capsule orally and diclofenac sodium suppository in combined group. The visual analogue scale (VAS), inflammatory factors, clinical efficacy and adverse reactions were observed at 6, 9, 12 h after the operation in the two groups. Results At 6, 12, 24 h after the treatment, the VAS was lower in the combined group [(3.8±0.5), (1.0±0.4), (0.8±0.4)] than that in the diclofenac sodium group [(5.2±0.7), (4.1±0.6), (3.6±0.5)] (P 0.05). Conclusion Postoperative pain and inflammatory response factors can be decreased with the use of Chinese alleviating pain capsule combined with diclofenac sodium suppository for patients with fracture after surgery, with higher safety and lower adverse reactions. Key words: Fracture, bone; Diclofenac; Pain, postoperative; Analgesia; Chinese alleviating pain capsule