Ranibizumab combined with grid laser photocoagulation for treating macular edema secondary to branch retinal vein occlusion

Objective To evaluate intravitreal Ranibizumab combined with grid laser photocoagulation for macular edema secondary to branch retinal vein occlusion (BRVO).Methods Ten eyes of 10 patients with macular edema associated with BRVO were included.Intravitreal bevacizumab was administered and then laser photocoagulation was performed 10 days later.The follow up was 2 weeks and 4 weeks.The best-corrected visual acuity(BCVA) and central macular thickness were measured after treatment and compared with baseline BCVA and central macular thickness.Results The mean baseline BCVA was 0.25 ± 0.12,and the mean central macular thickness was (465 ± 123) μm.The mean BCVAs at 2 and 4 weeks after treatment were 0.32 ± 0.16 (P =0.031) and 0.46 ± 0.13 (P =0.031) respectively.The mean central macular thickness at 2 and 4 weeks after treatment were (325 ± 89) μm (P =0.040) and (285 ± 50)μm(P =0.008).Conclusion Intravitreal Ranibizumab combined with grid laser photocoagulation can improve BCVA and alleviate macular edema. Key words: Ranibizumab;  Photocoagulation, laser;  Occlusion, vein, branch, retinal;  Edema,macular