Etiology and pathogenesis of idiopathic orbital Inflammatory pseudotumor

Idiopathic orbital inflammatory pseudotumor (IOIP) is a common ophthalmic disease that severely damages the visual acuity and countenance of the patient,its etiology and pathogenesis are unclear.Many hypotheses have been proposed,including infection,autoimmunity and neuroendocrine mechanism,etc..These hypotheses reflect certain aspects of the etiology and pathogenesis of IOIP and provide information for further understanding of the disease.The research progression in the etiology and pathogenesis of IOIP was reviewed. Key words: Idiopathic orbital inflammatory pseudotumor; Infection; Autoimmunity; Neuroendocrine