2009•Zhongguo linchuang shiyong yixueRequires access
The clinical study of combined Hemoperfusion+hemodialsi in chronic renal failure
yan li Peng
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Abstract
Objective To investigate the effect and safety of combined hemodialysis-resin hemoperf usion in chroicuremia.Methods 34 pailnets with chronic uremia were treated by combined hemodialysis-resin hemoperfusion.Middle molecular substances(MMS),urea and creatinine were detcted before and after the treatment.Meanwhile.we compared the effect of combined hemodialysis-resin hemoperfusion procdure with conventional hemodialysis in uremic toxin clearance.Results MMS was reduced significantly in combined hemodialysis-hemoperfusion procedure(P＜0.01).Compared with conventional hemoodialysis,a combination of hemoperfusion and hemodialysis had a better effect in MMS clearance(P＜0.01).Meanwhile,some clinical conditions (appetite,pruritus,insomnia)improved.we did not found any adverse effect.Conclusion as a method of MMS clearance,resin hemoperfusion Can effectively clean MMS and WaS confirmed to be a safand risk-free procedare.
Key words:
Hemoperfion; Hemodialysis; Chronic renal failure; Middle molecuular substances