Clinical pathological features and surgical treatment of primary intrahepatic cholangiocarcinoma

Primary intrahepatic cholangiocarcinoma (ICC) is the second frequent malignant tumor in adult liver, and appears an increasing tendency worldwide. Gross type is frequently mass-forming and a tubular adenocarcinoma is shown as the typical histopathological appearance. Surgical resection is the only curative treatment, and liver transplantation is selected for the patients with early ICC. Rediofrequency ablation, transcatheter arterial chemoembolization or molecular targeted therapies should be considered in the treatment of the unresectable or recurrent patients. Key words: Bile ducts, intrahepatic; Bile duct neoplasms; Pathology, clinical; Surgical therapy