Clinical analysis of vacuum sealing drainage combined with artificial dermis in repairing chronic wounds

Objective To observe the clinical efficacy of vacuum sealing drainage (VSD) combined with artificial dermis in repairing chronic wounds.Methods 66 cases of chronic wounds were randomly divided into control group and observation group,33 cases in each group.Control group was treated by antiinfection,microcirculation improvement,and wounds were covered by gauze soaked with povidone iodine cream with regular dressing change.Observation group was treated by anti-infection,microcirculation improvement and early vacuum sealing drainage (VSD),wounds were covered by artificial dermis (PELNAC) to induce dermal reconstruction after granulation tissue grew.Some bigger wounds were treated by skin grafting on base of satisfying growth of granulation tissue.Results In control group,the average hospital stay was (55.3 ± 1.2) days,30 cases received skin grafting or skin flap transplantation,wounds in 3 cases healed by wound dressing with remarkable scar formation.In observation group,the average hospital stay was (31.6 ± 1.2) days,bigger wounds in 20 cases were treated by skin grafting after wound bed preparation (granulation tissue growth) by artificial dermis,wounds in other patients were covered by artificial dermis with little scar formation.Conclusion Vacuum sealing drainage combined with artificial dermis in repairing chronic wounds can accelerate the healing speed of chronic wounds,reduce scar formation and shorten hospital stay. Key words: Vacuum sealing drainage (VSD);  Artificial dermis;  Repair;  Chronic wounds