2008•Zhongguo jiceng yiyaoRequires access
Analysis of the multi-resistance to antibiotics of clinical isolated klebsiella pneumoniae
Yuqiong Zheng, Shuzhen Chen, Yingmu Cai, Shao-wei Lin
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Abstract
Objective To investigate the multi-resistance to antibiotics of clinical isolated klebsiella pneumoniae.Methods The resistance to antibiotics of clinical isolated klebsiella pneumoniae were monitored.The discconfirmatory test was used to detect extended-spectrum β-lactamases(ESBLs) and cefoxitin three-dimension was used to detect AmpC β-lactamases.Results Among the isolates there were 53 strains of ESBLs-producing bacteria (49.5% ), 30 strains of AmpC-producing bacteria(28.0%), 24 strains of ESBLs + AmpC-producing bacteria (22.46%).They were high resistance to aminoglycosides,quinolones and cephalosporins.Conclusion The multi-resistance to antibiotics of clinical isolated klebsiella pneumoniae were widespread.It is important to control nosocomial infection to strengthen the detection of the epidemiology of ESBLs and AmpC β-lactamases in clinical isolates.
Key words:
Pneumoniae,klebsiella; Multi-resistance; ESBLs; AmpC β-lactamases