Progress of response evaluation and prognosis in chronic lymphocytic leukemia: reports from the 56th American Society of Hematology annual meeting
Ying Huang, Lei Fan, Wei Xu
Abstract
Ying Huang, Lei Fan, Wei Xu
Abstract
Chronic lymphocytic leukemia(CLL)is an incurable B cell chronic lymphoproliferative disorder with a highly heterogeneous clinical course. The malignant B lymphocytes that have a mature appearance infiltrate in to lymph node, bone marrow, liver and spleen. The 56th American Society of Hematology(ASH)annual meeting explored multiple aspects including pathogenesis, treatment, response evaluation and prognosis of CLL. Clinical outcome of CLL patients can be predicted more accurately by a series of novel markers such as minimal residual disease. The progress of response evaluation and prognosis in CLL were focused in this review. Key words: Chronic lymphocytic leukemia; Response evaluation; Prognosis; American Society of Hematology annual meeting
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Chronic lymphocytic leukemia(CLL)is an incurable B cell chronic lymphoproliferative disorder with a highly heterogeneous clinical course. The malignant B lymphocytes that have a mature appearance infiltrate in to lymph node, bone marrow, liver and spleen. The 56th American Society of Hematology(ASH)annual meeting explored multiple aspects including pathogenesis, treatment, response evaluation and prognosis of CLL. Clinical outcome of CLL patients can be predicted more accurately by a series of novel markers such as minimal residual disease. The progress of response evaluation and prognosis in CLL were focused in this review. Key words: Chronic lymphocytic leukemia; Response evaluation; Prognosis; American Society of Hematology annual meeting
Key concepts: Chronic lymphocytic leukemia, Hematology, Medicine, Internal medicine, Lymph node, Oncology, Bone marrow, Clinical pathology