A comparative study of narrow-band imaging amplification and chromoendoscopy magnifying in diagnosis of colorectal cancer and its precancerous

Objective To compare differential diagnostic value of narrowband imaging （NBI） mag nifying endoscopy and magnifying chromoendoscopy. Methods A total of 92 lesions from 75 patients were examined with conventional colonoscopy, NBI magnifying endoscopy and magnifying chromoendoscopy to e valuate pit patterns and vascular morphology patterns. Endoscopic findings were compared with the pathologi cal results. Results The detection rate of conventional endoscopy, NBI magnifying endoscopy and magnif ying chromoendoscopy were 94.6% （87/92）, 97.8% （90/92）and 100.0% （92/92）, respectively. NBI magnifying endoscopy was superior to the magnifying chromoendoscopy （ P = 0. 000） in the the lesion contour and microvessels pattern detection, but there was no difference in the pit patterns detected with the two tech niques （P = 0. 394）. Consistency, sensitivity, and specificity of NBI magnifying endoscopy in diagnosis of colorectal neoplastic lesions were 91.3% （84/92）, 83.9% （26/31）, 95.1% （58/61）, respectively, while these variables of magnifying chromoendoscopy were 89. 1% （82/92）, 80. 6% （25/31）, 93.4% （57/61）, which were not statistically significant （ P 〉 0.05）. Conclusion Differential diagnostic value of NBI magnifying endoscopy and magnifying chromoendoscopy for colorectal neoplastic and nonneoplastic le sions was similar, but NBI magnifying endoscopy displays the lesion contours and microvessels clearlier, and is easy to manipulate. Key words: Colorectal cancer;  Diagnosis;  Narrow-band imaging technology;  Staining amplification technology