Hemodynamic changes after selective decongestive devascularizatien shunt of gastrosplenic region in portal hypertension dogs

Objective To study the changes of hemodynamics after selective decongestive devas-cularization shunt of gastrosplenic region (SDDS-GSR) for treatment of portal hypertensive dogs. Methods SDDS-GSR were performed on portal hypertensive dogs. The portal venous pressure, he-modynamic parameters of portal vein, hepatic artery, spleen artery and vein were measured regularly. Results In 30 days after SDDS-GSR, the venous pressure in the gastrosplenic area decreased obvious-ly (P<0.01). Compared with those preoperative values, the parameters of blood flow in portal vein, splenic artery and vein markedly reduced (P<0.01) and the inner diameters of aforesaid vessels were narrowed (P<0.01), while the inner diameter and the parameters of blood flow in hepatic artery in-creased (P<0.01). In 60 days after the operation, the changes of aforesaid parameters were still sig-nificant as compared with those preoperative values (P<0. 01). Conclusion SDDS-GSR can decrease the venous pressure in the gastrosplenic area significantly while maintain portal perfusion by reducing the parameters of blood flow in splenic artery and ameliorating the resistance splenic vein blood cur-rent. It is reasonable and reliable for surgical management of portal hypertension. Key words: Hypertension,renal;  Splenic artery;  Distal splenorenal shunt;  Hemodynamics