Clinical progress of ketogenic diet in the treatment of intractable childhood epilepsy

Objective Ketogenic diet(KD)is one of the most important treatments of intractable childhood epilepsy.Its antiepileptic mechanism has been confirmed.With its wide application and dietary requirements, more selectable types have emerged.During the diet treatment, the combined use of antiepileptic drugs and vagus nerve stimulation, dietary adjustment and reduction of adverse reactions have gained certain clinical experience.In addition, the economic burden and quality of life for the treatment of ketogenic diet still need to be considered.Therefore, this article reviews the recent literature about ketogenic diet in the treatment of intractable childhood epilepsy and summarizes its clinical progress. Key words: Ketogenic diet; Children; Intractable epilepsy