2008Chinese Journal of AsthmaRequires access

Ion channels and hypoxia pulmonary vasoconstriction

Jue Wang, Hong Wang

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Abstract

Oxygen-sensitive ion channels widely expresses in pulmonary vascular smooth muscle cells,which determine vascular tone in hypoxia and are involved in hypoxia pulmonary vasoconstriction. The paper summarizes that roles of K+ and Ca2+ channels in acute and chronic hypoxia pulmonary vasoconstriction. Key words: Hypoxia pulmonary vasoconstriction;  K+ channels;  Ca2+ channels;  Hypoxia pulmonary hypertension

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What this paper is about

Oxygen-sensitive ion channels widely expresses in pulmonary vascular smooth muscle cells,which determine vascular tone in hypoxia and are involved in hypoxia pulmonary vasoconstriction. The paper summarizes that roles of K+ and Ca2+ channels in acute and chronic hypoxia pulmonary vasoconstriction. Key words: Hypoxia pulmonary vasoconstriction;  K+ channels;  Ca2+ channels;  Hypoxia pulmonary hypertension

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Available abstract

Oxygen-sensitive ion channels widely expresses in pulmonary vascular smooth muscle cells,which determine vascular tone in hypoxia and are involved in hypoxia pulmonary vasoconstriction. The paper summarizes that roles of K+ and Ca2+ channels in acute and chronic hypoxia pulmonary vasoconstriction. Key words: Hypoxia pulmonary vasoconstriction;  K+ channels;  Ca2+ channels;  Hypoxia pulmonary hypertension

Key concepts: Hypoxic pulmonary vasoconstriction, Vasoconstriction, Hypoxia (environmental), Medicine, Pulmonary hypertension, Cardiology, Internal medicine, Oxygen

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