Application of graded airway management during mechanical ventilation in neonates with acute lung injury

Objective To explore the application of graded airway management in mechanical ventilation of neonates with acute lung injury. Methods From June 2016 to June 2018, 84 cases of children with acute lung injury admitted to the neonatology department of this hospital were selected. According to the random number table method, the children were divided into the observation group and the control group, 42 cases of each group.The control group received routine airway management and chest physical therapy every 2 hours.The observation group received airway grading management according to the airway score of children.Acute physiological and chronic health scoreⅡ (APACHEⅡ), qi and blood indexes, mechanical ventilation time, hospital stay and complications were compared between the two groups before and 5 days after treatment. Results After treatment, tidal volume (VT), respiratory rate (f), and blood gas oxygen partial pressure (PaO2)/oxygen concentration (PaO2/FiO2) were significantly improved in the observation group compared with the control group, and the differences were statistically significant(P<0.05). APACHE Ⅱscore was significantly lower than that of the control group, and the difference was statistically significant(P<0.05). Mechanical ventilation time and hospitalization time in observation group were shorter than those in control group, and the differences were statistically significant(P<0.05). The incidence of ventilator-associated pneumonia was significantly lower than that of the control group, and the difference was statistically significant(P<0.05). Conclusions Airway grading management can effectively improve the respiratory function of children with mechanical ventilation in acute lung injury, reduce the incidence of ventilator-associated pneumonia in children, and promote the recovery of children. Key words: Airway grading management; Neonatal; Acute lung injury; Mechanical ventilation; Prognosis