The new advancement of high-frequency oscillatory ventilation in the treatment of acute respiratory distress syndrome

Background High-frequency oscillatory ventilation(HFOV) is an ideal lung-protective ventilation mode,which is more and more often used in adults with the acute respiratory distress syndrome (ARDS) remaining hypoxemic during conventional mechanical ventilation (CMV).Objective Though HFOV can improve oxygenation,the role of lung-protection doesn't play good.The aim of this paper is to reach consensus on an approach to HFOV that we thought would maximize its lung protective virtues while maintaining acceptable gas exchange and safety.Content In this review,we summarize the studies of HFOV and discuss the clinical experience using HFOV in adults in ARDS.Trend On the grounds of the results of more larger RCTs,HFOV should be reserved for patients failing conventional ventilation-based lung protective strategies.Before initiating HFOV,we should consider the consequences of heavy sedation and paralysis,hemodynamic changes and excessive noise. Key words: High-frequency oscillatory ventilation;  Acute respiratory distress syndrome;  Lung-protective ventilation