Current status of research and development of meningococcal vaccines
Yuan-xiang Jiang, Wei Zhu
Abstract
Yuan-xiang Jiang, Wei Zhu
Abstract
Meningococcal disease remains a major public health problem throughout the world,with associated high levels of morbidity and mortality.In this review,research and development of meningococcal vaccines and group B meningococcal vaccine in particular are discussed in the following aspects,including bacterial genetics,epidemic of meningococcal disease,vaccine supply,new candidate vaccines and new methods to identify meningococcal vaccine candidates. Key words: Neisseria meningitidis; Vaccines,conjugate; Outer membrane vesicle
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Meningococcal disease remains a major public health problem throughout the world,with associated high levels of morbidity and mortality.In this review,research and development of meningococcal vaccines and group B meningococcal vaccine in particular are discussed in the following aspects,including bacterial genetics,epidemic of meningococcal disease,vaccine supply,new candidate vaccines and new methods to identify meningococcal vaccine candidates. Key words: Neisseria meningitidis; Vaccines,conjugate; Outer membrane vesicle
Key concepts: Neisseria meningitidis, Meningococcal vaccine, Meningococcal disease, Medicine, Virology, Immunology, Biology, Bacteria