Research status on calorie restriction on glucose metabolism in patients with type 2 diabetes

Calorie restriction is one of the diet therapies for people with diabetes. Calorie restriction can reduce weight and improve glycemic control, but the long-term effects are controversial. The effects can be influenced by the degree of calorie restriction, the study duration, and the types of food used for intervention. The mechanism includes the improvement of β cell function and insulin sensitivity. The existing problems are compliance of patients, long-term effects, possible adverse effects, and the lack of high-quality studies. In this review, we introduced the current research progress of calorie restriction on glucose metabolism in patients with type 2 diabetes. Key words: Calorie restriction; Diabetes; Glucose Metabolism