Pathogenic mechanism of Angiostrongylus cantonensis
何汉江, 吴忠道, 余新炳
Abstract
何汉江, 吴忠道, 余新炳
Abstract
广州管圆线虫是一种人兽共患寄生虫,幼虫侵入人体后可移至大脑,主要引起嗜酸性粒细胞增多性脑膜脑炎.其发病为幼虫移行,幼虫在颅部占位并释放代谢产物,基质金属蛋白酶与纤溶酶原活化因子的产生,嗜酸性粒细胞对神经细胞的毒害及超敏反应等多因素作用的结果.偶尔该虫也可侵犯眼球,眼球病变主要是免疫反应导致的损害.了解广州管圆线虫的发病机制,对该病的防治和诊断具有重要意义。
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广州管圆线虫是一种人兽共患寄生虫,幼虫侵入人体后可移至大脑,主要引起嗜酸性粒细胞增多性脑膜脑炎.其发病为幼虫移行,幼虫在颅部占位并释放代谢产物,基质金属蛋白酶与纤溶酶原活化因子的产生,嗜酸性粒细胞对神经细胞的毒害及超敏反应等多因素作用的结果.偶尔该虫也可侵犯眼球,眼球病变主要是免疫反应导致的损害.了解广州管圆线虫的发病机制,对该病的防治和诊断具有重要意义。
Key concepts: Angiostrongylus cantonensis, Angiostrongyliasis, Mechanism (biology), Biology, Zoology, Helminths, Philosophy, Epistemology