The Research about the distribution of conjunctival sac bacterial flora & experiment of drug sensitivity before cataract surgery

Objective To research the distribution of conjunctival sac bacterial flora & experiment of drug sensitivity before cataract surgery,base on this research,provide the basis for clinical medication.Methods Collect Conjunctival sac of 205 eyes from 205 cases and make germiculture,observe the movement of positive Gram' s sensibility which effect by common antibacterial.Results There were 26 eyes with cultured positive Gram from 205 case,the ratio of positive was 12.68％.The preoperative conjunctival sac of cataract patients was mainly made up of Gram positive bacteria(96.15％),and most of them were Staphylococcus epidermidi(69.23％),there were also Staphylococcus haemolyticus,Staphylococcus chromogenes and Staphylococcus saprophyticus,Gram negative bacilli was the Pseudomonas cepaci.Most of grams were sensitive to Vancomycin,Amikacin,Teicoplanin,Clindamycin,Mupirocin,Furadantin and Morpholine trazodone,the tolerance was less than 20％,and they usually had higher tolerance to Cephalexin Penicillin,Tetracycline,Cefoxitin,Oxacillin and Erythromycin(more than 68％).Conclusion Staphylococcus epidermidis is the most common conditioned pathogen which exist in conjunctival sac before cataract surgery.We can choose common antibacterials such like Amikacin,Clindamycin,Furadantin for infection prevention or anti-infection. Key words: Cataract; Conjunctival sac; Bacterial culture; Antibiotic sensitivity