Surveillance and analysis of prognosis, APACHE II score and procalcitonin level in patients with severe pneumonia

Objective To Monitor and analysis of the relationship between prognosis and changes inprocalcitoninAcute Physiology and Chronic Health Evaluation(APACHE Ⅱ) and procalcitonin(PCT) levels in patients with severe pneumonia. Methods The clinical data of 123 patients with severe pneumonia admitted to the Department of Respiratory Medicine from June 2015 to June 2017 were compared.The differences in APACHE Ⅱ scores and PCT levels between the survival and death groups were compared. Results At 24 hours after admission, the APACHE Ⅱ score and PCT for the surviving group were (20.23±3.76) μg/L and (10.32±3.14) μg/L, respectively, and the death group was (24.47±4.15) μg/L and (12.24±2.84) μg/L.There showed significant difference in APACHE Ⅱ scores (P 0.05). APACHE Ⅱ and PCT levels in the survival group gradually decreased from 72 hours after admission to the end of treatment, while the death group gradually increased.There showed significant difference between APACHE Ⅱ and PCT between the two groups (P<0.05). Conclusions The PCT index is not sufficient to assess the prognosis of patients with severe pneumonia within 24 hours.The dynamic monitoring of APACHE Ⅱ and PCT can timely grasp the severity of the patient′s condition and deserves clinical attention. Key words: Pneumonia; APACHE; Procalcitonin