Control study of serum procalcitonin quantitative detection and blood culture results

Objective To study the clinical application value of quantitative detection of procalcitonin (PCT) in blood stream infections(BSI).Methods 620 patients with BSI were selected,they received PCT testing and inspection of whole blood culture tests.The results were compared.Results The positive rates of PCT detection and blood cultures were 32.42％ (201/620) and 29.68％ (184/620).The sensitivity,specificity,negative predictive value and positive predictive value of PCT detection were 90.97％ (564/620),63.06％ (391/620),82.34％ (345/419) and 54.73 (110/201).The species identification was conducted in 110 patients with positive PCT detection and blood cultures,42 cases were Gram negative (G-) bacteria,31 cases were Gram-positive (G +) bacteria,8 cases were fungi,29 cases were mixed infection,the difference of these four pathogens PCT concentrations was not statistically significant (x2 =2.364,P ＞ 0.05).Conclusion Quantitative detection of serum PCT in BSI patients has important guiding significance to early diagnosis. Key words: Procalcitonin;  Blood stream infections ;  Blood culture ;  Pathogens