Evaluation of effect of modified encephalo-duro-arterio-synangiosis on Moyamoya disease patients by single photon emission tomography
Gang Zhao, Shizhen Zhong, Jinhao Zhang, Yubao Wang
Abstract
Gang Zhao, Shizhen Zhong, Jinhao Zhang, Yubao Wang
Abstract
Objective To evaluate the effects of modified encephalo-duro-arterio-synangiosis (EDAS) on Moyamoya diseases (MMD) by single photon emission tomography (SPECT). Methods Thirty-six patients with MMD (29 with ischemic MMD and 7 with hemorrhagic MMD), admitted to our hospital from January 2011 to December 2013 and treated by modified EDAS, were chosen in our study; all the patients were followed up by SPECT, and the images changes before and after modified EDAS were compared. Results In the 36 MMD patients, 41 hemisheres were treated by modified EDAS; the total improvement rate was 56.1% (23/41), enjoying increased cerebral blood flow after EDAS; in ischemic MMD patients, the total improvement rate was 58.8% (20/34), while those was 42.9% (3/7) in hemorrhagic MMD patients. Conclusion The cerebral blood flow is improved obviously when MMD is treated by modified EDAS, especial on ischemic MMD patients. Key words: Moyamoya disease; Modified encephalo-duro-arterio-synangiosis; Single photon emission tomography
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Objective To evaluate the effects of modified encephalo-duro-arterio-synangiosis (EDAS) on Moyamoya diseases (MMD) by single photon emission tomography (SPECT). Methods Thirty-six patients with MMD (29 with ischemic MMD and 7 with hemorrhagic MMD), admitted to our hospital from January 2011 to December 2013 and treated by modified EDAS, were chosen in our study; all the patients were followed up by SPECT, and the images changes before and after modified EDAS were compared. Results In the 36 MMD patients, 41 hemisheres were treated by modified EDAS; the total improvement rate was 56.1% (23/41), enjoying increased cerebral blood flow after EDAS; in ischemic MMD patients, the total improvement rate was 58.8% (20/34), while those was 42.9% (3/7) in hemorrhagic MMD patients. Conclusion The cerebral blood flow is improved obviously when MMD is treated by modified EDAS, especial on ischemic MMD patients. Key words: Moyamoya disease; Modified encephalo-duro-arterio-synangiosis; Single photon emission tomography
Key concepts: EDAS, Moyamoya disease, Medicine, Single-photon emission computed tomography, Cerebral blood flow, Emission computed tomography, Radiology, Nuclear medicine